BABESJA - badanie i leczenie.j.angielski
Babesiosis causes an array of symptoms that change over time. You do not have to have all of the symptoms at once. Keep in mind, symptoms may change over time. In fact, symptoms of a Babesia infection could literally change every few minutes making you think you’re going crazy. It’s a stealth infection so you would not respond to a two week course of antibiotics like other typical infections. Babesiosis often requires 6 to 12 months of treatment, if not life-long herbal antimicrobials (after the drugs) in order to keep it at bay. Treatment varies from doctor to doctor.
There is a Part I to this article which you can read by clicking here, and it is more in-depth.
In the meantime, I will quickly list some of the classic symptoms before moving on to testing and treatment:There is a Part I to this article which you can read by clicking here, and it is more in-depth.
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Sweats. You might just get forehead droplets, or you may drench your clothes. This is not a hot flash.
* Thermal dysregulation. You feel hot, clammy and cold all at once.
* Headaches. Often these occur in the frontal region, or behind one (or both) eyes and unfortunately, you’ll get diagnosed with a “sinus headache” but it’s not.
* Mood problems. These range from mood instability, insomnia, depression, anxiety and bipolar.
* Dysautonomia. You may have the feeling of disequilibrium, or you may have gait disturbances and walk into walls a lot. You may have tinnitus.
* Heart palpitations. Cardiac irregularities are pretty hallmark and some of you may have POTS (postural orthostatic hypotension).
* Air hunger. It may get diagnosed as “asthma” or “shortness of breath” but it’s neither. It may feel like you can’t catch your breath.
* Déjà vu. This one is pretty hallmark, and it’s the sensation that you’ve already experienced an event, situation or conversation when in reality it is being encountered for the first time.
* Thermal dysregulation. You feel hot, clammy and cold all at once.
* Headaches. Often these occur in the frontal region, or behind one (or both) eyes and unfortunately, you’ll get diagnosed with a “sinus headache” but it’s not.
* Mood problems. These range from mood instability, insomnia, depression, anxiety and bipolar.
* Dysautonomia. You may have the feeling of disequilibrium, or you may have gait disturbances and walk into walls a lot. You may have tinnitus.
* Heart palpitations. Cardiac irregularities are pretty hallmark and some of you may have POTS (postural orthostatic hypotension).
* Air hunger. It may get diagnosed as “asthma” or “shortness of breath” but it’s neither. It may feel like you can’t catch your breath.
* Déjà vu. This one is pretty hallmark, and it’s the sensation that you’ve already experienced an event, situation or conversation when in reality it is being encountered for the first time.
Testing of Babesia
Ticks are by a mile the fastest way to catch Babesia, which comes with Lyme disease. It’s injected into you by one tick which almost always carries multiple organisms. Testing is hard I’ll be honest. There are only a couple of strains that are detectable from a blood test, so many physicians will diagnose you based upon clinical presentation, even if your blood test is negative.
Ticks are by a mile the fastest way to catch Babesia, which comes with Lyme disease. It’s injected into you by one tick which almost always carries multiple organisms. Testing is hard I’ll be honest. There are only a couple of strains that are detectable from a blood test, so many physicians will diagnose you based upon clinical presentation, even if your blood test is negative.
Babesia FISH Assay
Igenex offers this test. You can find more complex information about this (in case you’re a doctor) at the Igenex website. This is for direct detection of Babesia species (B. microti, B. duncani) using blood sample. The test is looking for RNA directly from the organism by dropping a fluorescent dye on the little glass slide with your blood smear. This is not an antibody (what I call a “shadow” test). The microscope magnifies the slide 1000 times using a specific filter for the selected dye to see if there is any RNA from the organism. Since, the rRNA (ribosomal RNA) is present in the organism, it causes the parasite to throw off a fluorescent signal. So if you have a FISH test, and if it’s positive then you have Babesia infection, whereas if it is negative you may still have Babesia because there are other species.
Babesia IgG/IgM (Babesia Microti or Babesia Duncani) IFA TestIgenex offers this test. You can find more complex information about this (in case you’re a doctor) at the Igenex website. This is for direct detection of Babesia species (B. microti, B. duncani) using blood sample. The test is looking for RNA directly from the organism by dropping a fluorescent dye on the little glass slide with your blood smear. This is not an antibody (what I call a “shadow” test). The microscope magnifies the slide 1000 times using a specific filter for the selected dye to see if there is any RNA from the organism. Since, the rRNA (ribosomal RNA) is present in the organism, it causes the parasite to throw off a fluorescent signal. So if you have a FISH test, and if it’s positive then you have Babesia infection, whereas if it is negative you may still have Babesia because there are other species.
This test is also offered by Igenex. It is for the detection of immunoglobulins of Babesia (specifically IgM and IgG antibodies). They use IFA or Immunofluorescent assay.
It’s an indirect test. Red blood cells from hamsters infected with Babesia parasites, are fixed on a glass slide then your serum is added. If Babesia-specific antibodies are present the slides will light up under the fluorescent-detecting microscope.
Positive Babesiosis titers are generally 1:160 or higher. Early in disease the titers may rise 4-fold to 1:2560. Later in disease the titer falls. This is a test your physician has to order just like the FISH test.
Other Lab FindingsIt’s not that any one of the following are indicative of Lyme, but taken together you may see results on labs indicating hemolytic anemia with reticulocytosis, thrombocytopenia, elevated bilirubin, elevated liver enzymes and/or reduced or absent haptoglobin. There could be proteinuria, and elevated BUN and creatinine in severe cases (where hemolysis is present).
Blood smears
Labs can can also look at hemolysis blood smears for diagnosis to specifically see the organism, it doesn’t work every time just sometimes. Multiple blood smears should be viewed. Babesia organisms are malaria-like protozoans that parasitize and reproduce within mammalian red blood cells that’s why they are sometimes seen in a blood smear. xxx The ring-like forms of Babesia are sometimes mistakenly confused with another parasite called “Plasmodium falciparum” so make sure trained staff is reading your smear.
Labs can can also look at hemolysis blood smears for diagnosis to specifically see the organism, it doesn’t work every time just sometimes. Multiple blood smears should be viewed. Babesia organisms are malaria-like protozoans that parasitize and reproduce within mammalian red blood cells that’s why they are sometimes seen in a blood smear. xxx The ring-like forms of Babesia are sometimes mistakenly confused with another parasite called “Plasmodium falciparum” so make sure trained staff is reading your smear.
Treatment of BabesiaDo I have a cure for you?
No. I’m sorry, I don’t have a cure, I don’t think anyone has a “cure” for Babesia based upon the fact that I cannot find one person who said “Dr So and So” cured me. I can’t find one physician who has a patient I can speak with that is “cured” although they have several patients that are doing better. There are treatments however, many treatments that can help improve quality of life. I believe in a multi-faceted approach, one that is broad-based and holistic, at least in part. In other words, I believe in a combination of various herbs and prescription medications as well as a healthy diet.
Since there are many treatment options offered by doctors, and they are not identical doctor to doctor (they are all vastly different), I’d like to give you some tips about all these things. I’m going to focus on supplements, herbs and medications that address Babesia symptoms and offer you better quality of life by reducing parasitic load. Keep in mind, these bugs are stealth, they hide and they come back after periods of remission. So maybe the “cure” is to keep them in remission for years at a time, instead of hours or days. Babesia is a parasite that is almost impossible to eradicate, but it is possible to feel a ton better and coexist.
Why is it almost impossible to eradicate? You have to kill the Babesia, but very carefully so you don’t kill yourself. It is a blood parasite. Imagine that every very time you kill an organism you blow up a red blood cell so you have to approach slowly and gently. No one I know can get this parasite load down to zero, maybe that’s why it’s hard to cure. I don’t know one doctor who can, and trust me, I know the best doctors on the planet. Brilliant, caring and wise… even they do not have a complete cure for Babesia yet.
My article today is not intended to treat, cure or diagnose anyone. If I had the answer to that I’d gladly give it to you because with all my heart I want you all to feel better.
So right now I’ll offer you information about what I know that could help. I can’t list everything in this single article, but I will continue to write about Lyme (and clan) if you stay with me. As I research and learn, I promise I will write more articles.
Your GENES
& SNPs
Ozone or “major autohemotherapy” is commonly used to treat Babesia, this is given by injection and it nudges your cells to produce higher amounts of superoxide dismutase or SOD. But what if you can’t do that? What if you are homozygous for an SOD snp? It’s going to be bad news for you because you will spark all these free radicals from the ozone (that is the point) but you will not be able to quell them because you can’t make adequate amounts of SOD. So if you have SOD snps, I don’t think you should do ozone, or peroxide or high dose vitamin C, or anything that is considered an oxidative therapy. You will raise your risk for cancer by taking these treatments if you don’t produce the SOD to neutralize the superoxide radicals spawned by the oxidative treatment. Now, what if you do not have a snp in the SOD producing enzyme? You might think you’re okay but I want you to think again. You see, the next compound made in that pathway is hydrogen peroxide. How do you know if you have enough catalase enzyme to break THAT down?! You will be making more and more peroxide and this is toxic to your cells. This stuff is really hard to tease out so let me just say this: If you do any kind of oxidative treatment and let’s assume it is done properly (slowly and at low doses, gently ramping up) and you feel terrible afterward, and you feel tired or have other odd symptoms pop up, I would say to stop it. This is your body’s way of telling you that you either have an SOD snp, or you do not have sufficient amounts of catalase on board. The catalase breaks down the peroxide and turns it into oxygen and water. Without enough catalase, you just build up peroxide which will ‘burn’ your insides (in my opinion).
Ozone or “major autohemotherapy” is commonly used to treat Babesia, this is given by injection and it nudges your cells to produce higher amounts of superoxide dismutase or SOD. But what if you can’t do that? What if you are homozygous for an SOD snp? It’s going to be bad news for you because you will spark all these free radicals from the ozone (that is the point) but you will not be able to quell them because you can’t make adequate amounts of SOD. So if you have SOD snps, I don’t think you should do ozone, or peroxide or high dose vitamin C, or anything that is considered an oxidative therapy. You will raise your risk for cancer by taking these treatments if you don’t produce the SOD to neutralize the superoxide radicals spawned by the oxidative treatment. Now, what if you do not have a snp in the SOD producing enzyme? You might think you’re okay but I want you to think again. You see, the next compound made in that pathway is hydrogen peroxide. How do you know if you have enough catalase enzyme to break THAT down?! You will be making more and more peroxide and this is toxic to your cells. This stuff is really hard to tease out so let me just say this: If you do any kind of oxidative treatment and let’s assume it is done properly (slowly and at low doses, gently ramping up) and you feel terrible afterward, and you feel tired or have other odd symptoms pop up, I would say to stop it. This is your body’s way of telling you that you either have an SOD snp, or you do not have sufficient amounts of catalase on board. The catalase breaks down the peroxide and turns it into oxygen and water. Without enough catalase, you just build up peroxide which will ‘burn’ your insides (in my opinion).
I realize that other people feel completely different and some people try to cure Lyme using peroxide. Please be nice and remember, this is my article, and my opinion. With Lyme there are ENOUGH cytokines and pro-inflammatory molecules, some people cannot handle any more, they simply cannot handle the backlash of peroxide because they do not have the catalase to dilute it back to water and oxygen. So please be real careful about using oxidative treatments, they help some people for sure, but not everyone.
Your Immune System
Your immune system has been hijacked. It doesn’t work like a regular uninfected person’s immune system. It over-reacts, it’s sensitive to everything, perfume, food, medicine, supplements… you should approach everything carefully and in low doses. If you’re sensitive, you may want to dump out 75 % of a capsule for some of your vitamins because a full dose will cause an adverse reaction. Baby doses are best until you know how you will respond.
Babesia infections know how to take over your immune system and turn it on you so you will have an assortment of autoimmune disorders, but the question is, “Are they all tied to Lyme or Babesia?” The other question is, “Does the medicine you take improve your immune function or does it weaken it some more?”
These are good questions to keep in mind as you undergo new treatments.
Herbal Antimicrobials
Not everything listed here is right for you, in fact, with Babesia, it is all about trial and error. Your physician should be in charge of your protocol, so don’t mistake my list as advice, it’s not. It’s just to shine a flashlight in the basic treatment protocol in case you are not responding to what you’re taking… well then you can ask doc about something you’ve learned about here. Just because it is over-the-counter, or natural doesn’t mean it won’t cause a herx or allergic reaction. Keep in mind, it’s really hard to kill Babesia, so interfering with life cycle with some of these herbs is ideal, the point is to slow, or stop their reproduction, then over time you feel better.
Not everything listed here is right for you, in fact, with Babesia, it is all about trial and error. Your physician should be in charge of your protocol, so don’t mistake my list as advice, it’s not. It’s just to shine a flashlight in the basic treatment protocol in case you are not responding to what you’re taking… well then you can ask doc about something you’ve learned about here. Just because it is over-the-counter, or natural doesn’t mean it won’t cause a herx or allergic reaction. Keep in mind, it’s really hard to kill Babesia, so interfering with life cycle with some of these herbs is ideal, the point is to slow, or stop their reproduction, then over time you feel better.
Cryptolepis.
This is an herb that one of my favorite Lyme experts, Steven Harrod Buhner talks about. It’s known as “Cryptolepis sanguinoleta.” Another friend and colleague, Dr. Richard Horowitz (cangetbetter.com) described how Cryptolepis was highly effective for one woman diagnosed with Babesia who kept relapsing after 5 years of various medications and herbs with anti-protozoal activity. Given that this herb is found in Ghana, demand for this herb often exceeds the supply in the USA. I buy this from Woodland Essences. If you take probiotics, and you should, there’s no concern about taking them along with cryptolepis, at the same time if you want.
This is an herb that one of my favorite Lyme experts, Steven Harrod Buhner talks about. It’s known as “Cryptolepis sanguinoleta.” Another friend and colleague, Dr. Richard Horowitz (cangetbetter.com) described how Cryptolepis was highly effective for one woman diagnosed with Babesia who kept relapsing after 5 years of various medications and herbs with anti-protozoal activity. Given that this herb is found in Ghana, demand for this herb often exceeds the supply in the USA. I buy this from Woodland Essences. If you take probiotics, and you should, there’s no concern about taking them along with cryptolepis, at the same time if you want.
Berberine.
Some people call it “Goldenseal” but I usually refer to it as Berberine. This natural compound is a strong antifungal. It also hits Babesia and a little bit of another malaria-like organism which I’m not going to elaborate on today called “Protomyxzoa rheumatica” or FL1953. This organism feeds on iron-rich hemoglobin so it will thicken your blood. They form very tight snuggly biofilms! You may feel better on an aspirin a day, or nattokinase or serrapeptase. Protomyxzoa can cause resistant hard-to-treat iron deficiency anemia. These bugs require lots of iron just like Babesia, but unlike Borrelia (Lyme) which requires lots of manganese as opposed to iron. If you have Lyme and an SNP in your SOD enzyme (which would necessitate the need for added manganese), it’s kind of like a one-two punch! You would really want to supplement with manganese (even low dose, not high) and of course, routinely check your RBC manganese levels. Back to berberine now… If you start taking berberine (or neem which comes up next) and you herx badly, worse than normal, it is possible that this is a stronger die-off due to the presence of undiagnosed Protomyxzoa.
Some people call it “Goldenseal” but I usually refer to it as Berberine. This natural compound is a strong antifungal. It also hits Babesia and a little bit of another malaria-like organism which I’m not going to elaborate on today called “Protomyxzoa rheumatica” or FL1953. This organism feeds on iron-rich hemoglobin so it will thicken your blood. They form very tight snuggly biofilms! You may feel better on an aspirin a day, or nattokinase or serrapeptase. Protomyxzoa can cause resistant hard-to-treat iron deficiency anemia. These bugs require lots of iron just like Babesia, but unlike Borrelia (Lyme) which requires lots of manganese as opposed to iron. If you have Lyme and an SNP in your SOD enzyme (which would necessitate the need for added manganese), it’s kind of like a one-two punch! You would really want to supplement with manganese (even low dose, not high) and of course, routinely check your RBC manganese levels. Back to berberine now… If you start taking berberine (or neem which comes up next) and you herx badly, worse than normal, it is possible that this is a stronger die-off due to the presence of undiagnosed Protomyxzoa.
http://suzycohen.com/articles/babesia-testing-and-treatment/
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BABESIA
Tiny parasites normally spread by ticks are increasingly sneaking into the US blood supply.
Called Babesia, the blood-loving parasites rarely kill. Many people don’t even have symptoms after an infection.
It’s not harmless, though. Babesiosis — the disease caused by Babesia — can be lethal to a class of people who need blood transfusions the most.
What’s more, there’s “no way of knowing” how many infected people are donating blood, according to a major blood donation center Tech Insider contacted. There’s also no large-scale, US government-approved way to test for Babesia in the 15.7 million blood donations transfused into 5 million Americans every year.
Those aren’t the only Babesia-related issues troubling the Food and Drug Administration (FDA), which oversees the US blood industry. Tick-borne babesiosis infections are on the rise and, in lock-step, so are those linked to blood transfusions. Even though it’s rare, babesiosis is the pathogen most often spread by blood transfusions, according to reports in The New England Journal of Medicine and Infectious Disease in Clinical Practice.
Thankfully, the FDA and other organisations are trying to do something about the growing threat.
Babesiosis isn’t caused by bacteria or viruses. Rather, one-celled parasitic animals called sporozoans are responsible. And of the 100-or-so known species, Babesia microti are the sporozoans that most often infect humans.
Once inside a person’s bloodstream, the microscopic creatures swim around until they find a red blood cell. They force their way inside, hijack the cell, and divide until it bursts. Then the sporozoans seek out new prey.
Red blood cells bursting with parasites are, of course, not good for you. Babesiosis typically causes headaches, chills, sweats, and a high fever within weeks or months of infection. (Except in an unknown fraction of people who don’t — but more on this shortly.)
http://www.businessinsider.com.au/babesia-parasite-increasing-threat-blood-donations-fda-test-2015-8
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BABESIA
Tiny parasites normally spread by ticks are increasingly sneaking into the US blood supply.
Called Babesia, the blood-loving parasites rarely kill. Many people don’t even have symptoms after an infection.
It’s not harmless, though. Babesiosis — the disease caused by Babesia — can be lethal to a class of people who need blood transfusions the most.
What’s more, there’s “no way of knowing” how many infected people are donating blood, according to a major blood donation center Tech Insider contacted. There’s also no large-scale, US government-approved way to test for Babesia in the 15.7 million blood donations transfused into 5 million Americans every year.
Those aren’t the only Babesia-related issues troubling the Food and Drug Administration (FDA), which oversees the US blood industry. Tick-borne babesiosis infections are on the rise and, in lock-step, so are those linked to blood transfusions. Even though it’s rare, babesiosis is the pathogen most often spread by blood transfusions, according to reports in The New England Journal of Medicine and Infectious Disease in Clinical Practice.
Thankfully, the FDA and other organisations are trying to do something about the growing threat.
A lurking danger
Almost all cases of babesiosis trace back to the bite of an infected deer tick, also called black-legged ticks. These are the same creepy crawlies responsible for the spread of Lyme disease — another tick-borne scourge experts have labelled an epidemic and a “public health fiasco.”Babesiosis isn’t caused by bacteria or viruses. Rather, one-celled parasitic animals called sporozoans are responsible. And of the 100-or-so known species, Babesia microti are the sporozoans that most often infect humans.
Once inside a person’s bloodstream, the microscopic creatures swim around until they find a red blood cell. They force their way inside, hijack the cell, and divide until it bursts. Then the sporozoans seek out new prey.
Red blood cells bursting with parasites are, of course, not good for you. Babesiosis typically causes headaches, chills, sweats, and a high fever within weeks or months of infection. (Except in an unknown fraction of people who don’t — but more on this shortly.)
http://www.businessinsider.com.au/babesia-parasite-increasing-threat-blood-donations-fda-test-2015-8
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